*When you buy through our links, we may earn a commission at no extra cost to you. Learn more.

15 Best Hybrid Strains | The Most Enjoyable Hybrid Weed Strains

best hybrid strains

Imagine relaxing on a comfy sofa while feeling utterly happy, without a care in the world. That’s precisely what some of the best hybrid strains of cannabis can do for you.

When Sativa and Indica strains join hands, they can make some of the most powerful and highly enjoyable strains. Since they give you the best of both worlds – excitement and relaxation at the same time – they’re enjoyed by a wide variety of people globally.

And the best part? There are thousands of hybrid strains to choose from that best fit your personality and preferences.

However, choosing between so many different cannabis options can quickly get confusing and frustrating.

So allow me to make your hybrid weed hunt a bit easier. Amongst thousands, I’ve narrowed down the list to eight of the best hybrid strains. These are the most popular and most loved – you’re going to have the best few hours of your life with them. Read on!


Best Hybrid Cannabis Strains



Banana OG Strain

Banana OG Strain

A tropical journey with Banana OG strain, a tantalizing Indica-dominant hybrid born from the union of OG Kush and Banana. Impressive 23% THC content.
ACDC Strain

ACDC Strain

ACDC strain good for therapeutic relief and recreational delight. Cross of Cannatonic and an undisclosed Ruderalis. With a low 1%THC and 13% CBD level
Cinderella 99 Strain Aka C99 or Cindy

Cinderella 99 Strain Aka C99 or Cindy

Cinderella 99 strain, a sativa-dominant that's pure magic in the cannabis realm. Cross of Jack Herer & Shiva Skunk, is a testament to breeding excellence.
Green Crack Strain | Invigorating!

Green Crack Strain | Invigorating!

Green Crack strain a sativa-dominant strain cross of Skunk #1 and Afghani landrace, bursts onto the scene with a THC content ranging from 16% to 24%.
Tarantula Strain

Tarantula Strain

The Tarantula Strain is an Indica-dominant hybrid that seamlessly melds genetics from Cookies Gelato & Skunk to deliver a truly exceptional experience.
Wabanaki Strain

Wabanaki Strain

Wabanaki strain is renowned for its energizing effects and therapeutic potential. This sativa-dominant hybrid delivers a truly unique experience.


What Is a Good Hybrid Strain?

Hybrid cannabis strains possess Sativa and Indica genetics with effects of both. Some hybrids may be Sativa dominant, while others may be high Indica strains.

However, the one having a balanced combination of Indicas and Sativas is considered to be a good hybrid cannabis strain. These types of strains help you get the best of both the Sativa and Indica worlds resulting in the best weed strains.


What Are the Benefits of Hybrid Strains?

By and large, the effects of a hybrid strain depend on whether it’s a Sativa or Indica dominant. Cannabis Sativa dominant marijuana buds will impart energy and focus in you, whereas Indica dominant ones will help you relax and sleep peacefully. In addition, a balanced hybrid cannabis strain has similar effects to both Sativas and Indicas.


Is Hybrid an Upper or Downer?

Hybrid strains can be upper or downer, mainly depending on their dominant species. Moreover, you have to study your strain’s cannabinoids closely to get an answer. Generally, an upper has more uplifting and energizing effects, while a downer relieves anxiety and induces sleep.


Hybrid Weed Strains Reviews

My hybrid strain picks have a few Sativa dominant hybrid strains, while others are Indica dominant. Trust me; you won’t be disappointed with these award-winning picks:


1. Original Glue – OG

Original Glue best hybrid strain

​A quick fix to a restless and sleepless night, the Original Glue, also known as Gorilla Glue #4, is one of the most potent Indica dominant hybrid strains. Its whopping 30-32% THC content makes sure you relax and sleep a wonderfully dreamy night.

With multiple awards to its name, Original Glue first hits you with a cerebral rush, erasing all signs of worries and sadness. Once you’re all happy and laughing, expect to get ‘stuck’ to your couch for hours, as the highly potent Indica relaxes your body.

With a mix of diesel, chocolatey, and earthy flavors, the very sought-after Original Glue is commonly used for sleeplessness, depression, and stress. However, dryness of the mouth and eyes are two main side effects of this beautiful cannabis plant.


2. Runtz


A hybrid cannabis strain, Runtz has equal amounts of Indica and Sativa, i.e., 50%. It was made possible after a cross between Zkittlez and Gelato strains.

This marijuana strain smells sweet, just like candy, a feature primarily because of its terpene profile. In addition, the taste is also sweet with a fruity and earthy undertone. The THC content in Runtz is super high that averaging between 19%-29%.

Overall, a strong wave of euphoria hits you hard soon after you smoke Runtz, starting from your head and gradually spreading throughout the body. Its high lasts for hours until it puts you in a deep calming sleep. In addition, due to its high THC level, it can be effective against insomnia, chronic pains, stress, and anxiety.


3. Gelato – Hybrid Weed Strain

gelato hybrid strain

Imagine devouring a gelato cone that makes you soar high without adding any extra pounds to your body. The deliciously creamy and sweet Gelato strain does something very similar, leaving you in a dream-like state.

With 20-25% of THC and being one of the most sought-after cannabis Indica dominant strains, this dreamy hybrid weed induces a surprising amount of high. The fast-acting cerebral rush, which makes you super happy, social, and worry-free, slowly spreads into the body.

However, it doesn’t leave you couch-locked – you can spend the day doing your daily tasks with a happy mind and relaxed body. The balanced effects of Gelato make it a strain you must try at least once in your life.


4. GMO-Cookies

GMO Cookies

Also famous as Garlic Cookies, GMO-Cookies is an Indica dominant hybrid strain developed after a cross between two potent cannabis strains, i.e., Chemdawg and Girl Scout Cookies.

The cannabis strain is widely infamous for its pungent smell and a hard high among Indicas lovers. Moreover, it has a garlic taste with a sour and spicy exhale that stays on your palette for some moments after your final stoke.

Just like its taste and aroma, the high is long-lasting too. It is among those hybrid marijuana strains that will keep you flying high for hours. Due to these calming, uplifting effects and high THC content, this strain is highly beneficial in conditions such as depression, pain, stress, and insomnia.


5. GSC – Girl Scout Cookies

girl scout cookies strain

The Girl Scout Cookies is a celebrity in the cannabis world (seriously. Every stoner knows about it!). This super potent strain is well-known to work for patients with depression and anxiety. It can also help ease muscle spasms and chronic pain.

This is possible due to the long-lasting effects of cannabis Indica and Sativa in GSC. The 25-28% of THCs and 1% of CBD induce euphoria that dissolves into a relaxed, couch-locked mind and body. These high Indica strains can fight chronic pain effectively and even give you munchies.

With a sweet, creamy taste and smoke, this couch-locking yet mind-soaring strain has become the go-to hybrid weed for thousands (including rappers).


6. Sunset Sherbert

sunset sherbet

This one is for those who want the best of both cannabis Sativa and Indica. A hybrid of Girl Scout Cookies and Pink Panties strains, this Indica dominant strain gives you an energizing high and super bodily relaxation.

Sunset sherbert gives out a sweet honey-like smell, and after burning, it tastes like a sweet yogurt and honey with an earthy undertone. Although the THC level in this hybrid cannabis strain is moderate (15%-19%), its effects are still very much like the other Indica strains.

After consuming the strain, you’ll feel uplifting sensations with a full-body buzz which ultimately brings you at ease. Moreover, it has an effect on your body pains and mental agony or stress.


7. Wedding Cake

wedding cake hybrid

Another of the most balanced hybrid marijuana strains, Wedding Cake, offers you the best of both worlds. It almost instantly hits you with a buzz in the head, giving you long-lasting euphoria.

While making you focused, it might also make your thoughts race. This, in the right setting, can lead to creative ideas and spark deep conversation.

After a comparatively long high, your body finally goes into blissful numbness. It might even result in a couch lock due to the high level of THC, but your brain will still maintain thoughtfulness and creativity.

Unlike its name, Wedding Cake has a harsh smell but a creamy and sweet taste that pleases the taste buds.


8 Sundae Driver

Sundae Driver

Sundae Driver is a cross between Fruity Pebbles and Grape Pie strains with a sweet and fruity flavor. If you’re a consumer who likes a chocolate sundae, you’ll be ecstatic over this hybrid marijuana strain.

The light-green and purple buds of this cannabis plant are blanketed in between trichomes having high THC concentrations. THC levels in the Sundae Driver range between 14%-16% generally.

Similar to its taste, the aroma also has an earthy and sweet grape candy-like profile with a chocolaty overtone. In terms of effects, those types of cannabis strains make you feel calmer and happier after entering your system. Moreover, its also seen to have excellent medical usage for chronic pains, PTSD, etc., due to its genetics.

Buy Seeds Online


9. Blue Cookies

Blue Cookies strain

An offspring of the famous Girl Scout Cookies and Blueberry, Blue Cookies is a potent yet well-balanced hybrid strain. Even though it isn’t a cannabis Sativa dominant hybrid strain, it induces a very intense buzz in the head, leading to paranoia in large doses.

However, the high lasts a short while, as a heavy numbness soon takes over the body, making it ideal for patients with chronic pain.

Blue Cookies is ideal for day and night with a taste full of sweet berries and sometimes with dank undertones.


10. Mimosa


Mimosa is a Sativa dominant hybrid strain produced by crossing Clementine and Purple Punch strains. Like other Sativa strains, Mimosa also offers you a bombardment of energy and focus throughout the day.

Having a high THC level of around 27%, the entourage effect of this marijuana hybrid is quite robust. It fills you up with an energy rush and happiness. In addition, the clear-headedness and extra focus imparted by this strain help you get through the day. However, dry mouth is one of the side effects of these Sativas.

Overall, these cannabis Sativa strains have a delicious and sweet citrusy taste along with a light berry exhale that feels just like a fresh mimosa.


11. Mac 1

mac 1 hybrid strain

Need to feel pure happiness? The Mac 1 can give you exactly that, along with a relaxed body, as it’s the most perfectly balanced hybrid cannabis strain out there.

With around 20-23% of THCs (and sometimes even more), it makes you feel joyful and calmly euphoric, driving any dark thoughts away from the mind. After a while, deep relaxation sets in the body, which often leads to couch-lock.

Considering its ideally balanced genetics and effects, it could be a suitable replacement for your evening glass of alcohol. Plus, the sour, fuel-like taste balanced with a spicy, citrusy taste makes it an exciting and adventurous choice for the palate.


12. Cereal Milk

Cereal Milk

Cereal Milk is one of these cannabis types that has evenly balanced Sativa and Indica ratios. This marijuana strain is a hybrid of strong Snowman and Y-Life Strains.

Typically, its delectable tang and aroma resemble fruity sweet cereal milk. In addition, you’ll get a hint of berries and creamy sugar all along while consuming this hybrid strain.

Apart from its unique taste and smell, its cured buds are a site to watch. They depict multiple shades of green and pale yellows. Many users claim that its results make them calm and relaxed and enhance their focus and energy.


13. Motorbreath

Motorbreath hybrid

For veteran stoners looking for more robust and exciting flavors, the award-winning Motorbreath is an excellent place to start.

Why? Well, for one, it tastes and smells like soil, fuel, garlic, and even meat (no, I’m not kidding!). Secondly, these cannabis buds have an average THC of 28%, sometimes going over even 30%. This, as you can imagine, can give you a mind-boggling amount of high.

Motorbreath hits you with an intense euphoria without the energetic side effects. After that, you’ll find yourself profoundly couch-locked and dozing off. Hence, it’s the perfect hybrid strain for night use. But mind you, it’s only suitable for the experienced!


14. Blue Dream

Blue Dream

A Sativa dominant strain, Blue Dream takes you on a stroll on clouds high in the sky with its super mild euphoric effects. Primarily, it was created through a cross between Blueberry and Haze cannabis strains.

The taste of this Sativa dominant marijuana strain is an excellent reason behind its huge fan following. It has a sweet taste like berries and an aroma similar to a blueberry pie. In addition, the flavoring stays on your tongue for some time after inhaling these Sativas.

On average, the THC contents of these cannabis plants remain between 17%-24%. Moreover, the properties of both its Indica and Sativa parents are highly reflective in its effects. A high-quality Blue Dream cannabis strain will impart an uplifting cerebral high with an energy rush throughout your body. That’s the reason it is also considered of quite a help in various health conditions.


15. White Widow

White Widow hybrid strain

A trichome-heavy strain that hits you hard with a cerebral rush, White Widow is one fast-acting hybrid weed. It has average THC levels of 20%, sometimes reaching even higher.

Even though this strain has an underwhelming earthy and piney flavor, it’s one of the most popular Sativa dominant hybrid strains out there. With a boost of energy, you’ll find yourself highly focused and super alert. It’ll also give you the ability to explore new realms of creativity.

A word of caution, though: the mind-racing, psychedelic effects of the White Widow might make you borderline paranoid. Hence, go easy on the dosage with this hot-headed strain.


Wrapping Up with the “Best Hybrid Strains”

What’s the best hybrid strain for you? The answer depends on the effects you’re looking for and the taste profiles that suit your taste buds. Both Sativas and Indicas have their benefits.

For the adventurous who are looking for some whacky after-effects, Sativa-dominant hybrid strains are the best picks. Something like White Widow or Mac 1 can leave you giggling and imagining strange things – a feeling worth experiencing.

But for some deep relaxation, Indica dominant hybrid strains like Blue Cookies and GSC can make you pain-free and blissfully sleepy.

Moreover, the taste and aroma of a marijuana hybrid strain is another thing to consider – not everyone enjoys sickly sweet buds or intense, chemical-y flavors. Lastly, you’ll have to note the cannabinoid levels, i.e., THC and CBD (cannabidiol) in your buds. How potent a strain can you tolerate?

Typically, I suggest novices start with something well-balanced like Gelato. It lets you enjoy the high and relaxing effects without agitation or disorientation. When you’ve had enough experience, you can move on to exploring more potent cannabis buds.

Skip to content